Human STING is a proton channel

Science

Co-discovered a novel function for the STING immune sensor as an ion channel required for non-canonical autophagy and inflammasome activation.

Ebola Virus Optical Pooled Screen

Nat Microbiol

Genome-wide image-based screen identifying novel host regulators of Ebola infection via deep learning classification of viral stages.

STING Trafficking Screen

Cell Systems

Genome-wide optical pooled screen studying STING intracellular trafficking, identifying novel regulators via SVMs across 45M cells.

IRF3 Translocation Screen

PNAS

First genome-wide optical pooled screen, identifying modulators of IRF3 nuclear translocation upon Sendai virus infection.

PhD Thesis

Thesis 2023

Doctoral thesis (HST 2023).